Abnormal cisternogram associated with Diamox therapy.

N Papanicolaou; B J McNeil; H H Funkenstein; L R Sudarsky

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PubMed · 641572

Abnormal cisternogram associated with Diamox therapy.

N Papanicolaou·B J McNeil·H H Funkenstein·L R Sudarsky

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Abstract

A cisternogram characteristic of normal-pressure hydrocephalus was obtained from a patient on Diamox who was being evaluated for rapid mental deterioration. A repeat cisternogram after Diamox was discontinued was nearly normal. We hypothesize that the initial abnormality resulted from reduced cerebrospinal fluid production caused by carbonic anhydrase inhibition; this defect (reduced flow) led to a net reflux of tracer into the ventricles. The reflux is believed to be due to the reduction of bulk cerebrospinal fluid from the ventricles.

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N Papanicolaou, B J McNeil, H H Funkenstein, L R Sudarsky. 1978. Abnormal cisternogram associated with Diamox therapy.. https://pubmed.ncbi.nlm.nih.gov/641572/

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