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PubMed · 6462911

Fast computer search for similar DNA sequences.

M Bishop·E Thompson
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Abstract

An extremely fast method of searching a nucleic acid sequence database against a probe sequence is described. The method is based on the detection of deviation from expected number and deviation from random spatial distribution of sub-sequences which are unique within a sequence, and shared between that sequence and the probe. On an IBM 3081 computer, total search of an encoded form of the EMBL nucleic acid sequence database with a 1 kbase probe sequence is completed in a few seconds. Previous best methods for a similar task required a few minutes.

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AnimalsBase SequenceChickensComputersDNAHumansMiceProbabilityRabbitsSpecies SpecificityJournal ArticleResearch Support, Non-U.S. Gov't

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M Bishop, E Thompson. 1984-07-11. Fast computer search for similar DNA sequences.. https://doi.org/10.1093/nar%2F12.13.5471

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