A solid phase antibody screen.

F V Plapp; L T Sinor; J M Rachel; M L Beck; W M Coenen; W L Bayer

doi:10.1093/ajcp/82.6.719

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PubMed · 6507384

A solid phase antibody screen.

F V Plapp·L T Sinor·J M Rachel·M L Beck·W M Coenen·W L Bayer

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Abstract

An automated solid phase antibody screen (SPAS) in microplates has been developed. Red blood cell (RBC) adherence was used as the end point instead of agglutination. Consequently, positive and negative reactions were readily distinguished by a microplate spectrophotometer. The SPAS performed as well as conventional antiglobulin methods for detecting IgG antibodies in donor sera and had increased sensitivity as determined by serial dilutions of antibodies.

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F V Plapp, L T Sinor, J M Rachel, M L Beck, W M Coenen, W L Bayer. 1984. A solid phase antibody screen.. https://doi.org/10.1093/ajcp%2F82.6.719

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