PubMed HealthSearch

PubMed · 654445

[Chondrosarcoma. (An electronmicroscopic study) (author's transl)].

Abstract

The ultrastructure of 6 chondrosarcomas was analysed. These areas which by means of light microscopy appear benign, displayed the same appearance as chondromas. Malignant areas are characterised by distined variation of cells, nuclei and nucleoli. There is an electron-dense zone of 400 A between the inner membrane of the nucleus and the chromatic in some nuclei containing dense chromatin. The amount of cytoplasmatic organellae decreases as differentiation decreases. Nevertheless there are sometimes cells with an unusual accumulation of cytoplasmic organellae.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

W Wenkelmann, W Becker, M Cserhati. 1978. [Chondrosarcoma. (An electronmicroscopic study) (author's transl)].. https://pubmed.ncbi.nlm.nih.gov/654445/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

The WHO Histological Typing of Odontogenic Tumours. A commentary on the Second Edition.

This article introduces the revised World Health Organization (WHO) classification of odontogenic tumors and jaw cysts and certain bone lesions that either are peculiar to the jaws or have distinctive features in that location. The new and revised classification is compared with the previous version, the reasons for the changes are outlined, and reference is made to a number of newly characterized lesions that have been included.

Bone Neoplasms

[MR imaging of bone metastasis].

One hundred and three patients with known malignancy and suspected bone metastasis underwent magnetic resonance imaging. In 93%, the metastatic lesions, detected both on plain films and radionuclide bone scans, showed decreased signal intensity on T1-weighted images and increased signal intensity on T2-weighted images. All lesions, except one lesion showing much blastic change on plain films, showed contrast enhancement with Gd-DTPA administration. Although further investigation is needed, a correlation between the type of primary malignancy and the signal intensity of the metastatic lesion is suggested. Among 312 metastatic lesions detected by MR imaging, 272 lesions (87%) and 134 lesions (40%) were also detected by radionuclide bone scans and plain films, respectively. In five cases, MR imaging clearly revealed the lesion compressing the spinal cord, which helped us formulate a therapeutic plan. We conclude that MR imaging is the most sensitive examination for detecting bone metastasis and is necessary for planning treatment.

Bone Neoplasms