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PubMed · 6589020

Variable breakpoints on Ph1-chromosome.

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R S Verma, H Dosik. 1984. Variable breakpoints on Ph1-chromosome.. https://pubmed.ncbi.nlm.nih.gov/6589020/

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Philadelphia-positive T-acute lymphoblastic leukemia.

A case of typical T-acute lymphoblastic leukemia (T-ALL) is reported in which, at diagnosis, 100% of bone marrow metaphases showed a Philadelphia (Ph) translocation, t(9;22). These cells completely disappeared following chemotherapy. The significance of the Ph chromosome in T and B leukemic cells is discussed.

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