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PubMed · 6590113

Prolymphocytic leukemia. Serial responses to therapy.

J F Swift·H G Wold·D R Gandara·J Redmond·C B George
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Abstract

Prolymphocytic leukemia is a rare lymphoproliferative disorder characterized by marked lymphocytosis, massive splenomegaly, minimal lymphadenopathy, and poor prognosis. Previous reports have noted very short survival, and poor response to single agent alkylator chemotherapy. A small number of reports have shown response to combination chemotherapy regimens including Adriamycin (doxorubicin). A case of prolymphocytic leukemia with serial responses to combination chemotherapy and splenectomy resulting in significant prolongation of survival is reported.

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Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDoxorubicinFemaleHumansLeukemia, LymphoidMiddle AgedPrednisoneSplenectomyVincristineCase ReportsJournal Article

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J F Swift, H G Wold, D R Gandara, J Redmond, C B George. 1984-09-15. Prolymphocytic leukemia. Serial responses to therapy.. https://doi.org/10.1002/1097-0142(19840915)54%3A6%3C978%3A%3Aaid-cncr2820540605%3E3.0.co%3B2-h

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