PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 666262

Ventricular volume in man computed from CAT scans.

R D Penn·M G Belanger·W A Yasnoff
View original source ↗Export metadata ↓

Abstract

A new interactive computers has been developed to measure ventricular volume from CAT scans. Testing this system on phantoms demonstrated an accuracy to within 16%. Then a series of scans of patients with obstructive hydrocephalus was analyzed using both tradional linear measures and the computer method. None of the traditional measures were directly proportional to the calculated volume. The area measure of ventricular volume correlated well with the computer-generated values. Clinical studies which attempt to quantitate ventricular volume should use a computerized or planigraphic measure.

Explore related subjects

Cerebral VentriclesComputersHumansHydrocephalusModels, StructuralRadionuclide ImagingJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

R D Penn, M G Belanger, W A Yasnoff. 1978. Ventricular volume in man computed from CAT scans.. https://doi.org/10.1002/ana.410030306

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Comparison of intracranial pressure measured simultaneously within the brain parenchyma and cerebral ventricles.

We report a 48-year-old man treated for acute subarachnoid hemorrhage (SAH) wherein intracranial pressure (ICP) was measured simultaneously within the ventricular cerebrospinal fluid (CSF) and the brain parenchyma (PAR). Single pressure waves within the continuous pressure signal were identified with determination of the single wave parameters pulse amplitude (i.e. pressure difference between diastolic minimum pressure and systolic maximum pressure), mean pressure (i.e. mean pressure from beginning to ending minimum diastolic minimum pressure), and latency (i.e. rise time from diastolic minimum pressure to systolic maximum pressure). A total of 218,589 CSF/PAR single pressure wave pairs were analyzed. For these CSF/PAR wave pairs the mean difference in pulse pressure amplitude was -0.13 mmHg [95% confidence interval (CI) -0.13 to -0.12 mmHg], mean difference in mean single wave pressure -0.71 mmHg (95% CI -0.74 to -0.68 mmHg), and mean difference in latency -0.01 seconds (95% CI -0.01 to -0.01 seconds). Hence, in this patient monitoring ICP within the ventricular CSF or brain parenchyma gave similar results. Moreover, the comparisons of single CSF/PAR wave pulse pressure amplitudes gave no evidence of a pressure gradient from brain parenchyma to the ventricular CSF in this patient.

Cerebral Ventricles↗
PubMed2006

Periventricular nodular heterotopia and Williams syndrome.

We report here on the first case of a child with bilateral periventricular nodular heterotopia (PNH) and Williams syndrome. Fluorescent in situ hybridization (FISH) analyses demonstrated a deletion of the elastin gene in the Williams syndrome critical region (WSCR). Further mapping by loss of heterozygosity analysis both by microsatellite marker and SNP profiling demonstrated a 1.5 Mb deletion beyond the telomeric end of the typical WSCR. No mutations were identified in the X-linked filamin-A gene (the most common cause of PNH). These findings suggest another dominant PNH disorder along chromosome 7q11.23.

Cerebral Ventricles↗