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PubMed · 6687152

[Primary glaucoma and the laser].

Abstract

The use of the laser for treatment of different forms of primary glaucoma is proposed. In closed-angle glaucoma its use is limited to those cases where a large part of the angle is capable of ensuring drainage of aqueous humor. Pupilloplasty could be an alternative to iridotomy for relieving pupillary blockage. Peripheral circular gonioplasty can enlarge the angle. Finally, the laser can reduce ciliovitreolenticular blockage in malignant glaucoma. In patients with open-angle glaucoma, trabeculoplasty should be performed in the interval between medical and surgical treatments. Initial results appear promising but further study is necessary to evaluate the value of this type of therapy.

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BibTeXRIS

R Etienne. 1983. [Primary glaucoma and the laser].. https://pubmed.ncbi.nlm.nih.gov/6687152/

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Model of pulsatile-flow of aqueous humor through the iris-lens canal.

PURPOSE: To present a model of pulsatile-flow of aqueous humor from posterior (PC) to anterior chamber (AC) and to analyze the sensitivity of this novel model in detecting typical high risk conditions predisposing to pupillary block. METHODS: The model assumes noncontinuous flow of aqueous through the iris-lens canal. Aqueous that fills the canal will be ejected toward the AC-side of the canal at certain time intervals, and between 2 events of aqueous ejection there is no actual flow through this canal. Pupillary pumping rate (PPR) was calculated from the aqueous flow rate and the calculated volume of iris-lens canal. RESULTS: PPR values were generated by incorporating pupillary diameter (1 to 8 mm), aqueous flow rate (1 to 2.5 microL/min), and iris-lens canal width (0.5 to 2 mm) and height (3-9 microm) in numerical experimentation with the present model. PPR showed inverse dependence on iris-lens canal height and pupillary diameter and was directly proportional to aqueous flow rate, in agreement with the steady-flow model. However, contrary to the steady-flow model, PPR showed inverse dependence on iris-lens canal width and predicted the anticipated PC-AC pressure gradient changes at simulated light-dark transition in eyes of patients with clinically narrow angles and ultrasound biomicroscopy evidenced pupillary block. CONCLUSIONS: Upon the incorporation of real ultrasound biomicroscopy measurements in numerical experimentations with both models, the present pulsatile-flow model, contrary to the steady-flow model, showed good predictability of PC-AC pressure gradient changes in a typical condition predisposing to pupillary block.

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