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A microcomputer system for measuring neuron properties from digitized images.

R R Mize
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Abstract

A microcomputer system has been developed for the quantitative analysis of neurons, synapses, and other biological profiles. The outlines of profiles are traced from micrographs using a digitizer. From these traces, the system calculates cross-sectional area, perimeter (length), average diameter, and form factor. Data values for the number of profile contacts, the number of elements within a profile, the number of elements associated with a profile, profile type, and profile depth are also entered. The program calculates contact and element densities from these values. The data are printed-out on a thermal printer and stored on magnetic tape or floppy disk. The software is written entirely in BASIC. The system uses commercially available hardware, including a Hewlett-Packard 9845T microcomputer and H-P 9874A digitizer. The programs can be adapted to a wide variety of other microcomputer systems.

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AnimalsBrainCatsComputersMicrocomputersMicroscopy, ElectronNeuronsRetinaSoftwareSuperior ColliculiSynapsesSynaptic VesiclesVisual PathwaysJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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R R Mize. 1983. A microcomputer system for measuring neuron properties from digitized images.. https://doi.org/10.1016/0165-0270(83)90124-3

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