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PubMed · 6709881

[Coumarin embryopathy].

F E Struwe·H Reinwein·R Stier
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Abstract

Anticoagulant therapy using coumarin derivatives (vitamin K antagonists) during early pregnancy may result in a characteristic embryopathy appearing as a phaenocopy of chondrodysplasia punctata (Conradi-Hünermann's disease). This has been suggested in advance by observations made in newborns of mothers who had been treated previously with warfarin or acenocoumon. Similar observations made in a newborn after the mother's treatment with phencoumon in early pregnancy are described in this paper. Coumarin embryopathy is proposed as a common term.

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Chondrodysplasia PunctataCoumarinsFemaleHumansInfant, NewbornMaternal-Fetal ExchangePregnancyRadiographyCase ReportsJournal Article

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F E Struwe, H Reinwein, R Stier. 1984. [Coumarin embryopathy].. https://pubmed.ncbi.nlm.nih.gov/6709881/

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