PubMed Health⌕ Search

PubMed · 6748977

[Campylobacter jejuni gastroenteritis].

Abstract

Acute gastroenteritis is a major cause of hospital admission with attendant morbidity and occasional mortality. Campylobacter jejuni recently has been recognized as a common cause of acute bacterial gastroenteritis in children and adults. Its frequency of isolation is comparable to and in many studies exceeds that of Salmonella isolations from diarrheal stools of hospitalized patients. Medical workers in many parts of the world confirmed that Campylobacter jejuni was found more commonly in feces in diarrheic than in non-diarrheic people. The feces is loose to watery and commonly contains blood and leukocytes. Although, Campylobacter jejuni has been isolated from feces and gallbladder of healthy and diarrheic animals, until now, to our knowledge, there is no report on the isolation of the microorganism from healthy or diarrheic subjects in Turkey. This paper reports three human infections found to have Campylobacter jejuni in their stools as part of our ongoing investigation of the incidence of diarrheal disease due to this organism.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

I Tezcan, M Ceyhan, S Diker, A M Tuncer, E Dağli, E Kinik. 1984. [Campylobacter jejuni gastroenteritis].. https://pubmed.ncbi.nlm.nih.gov/6748977/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

The O-specific polysaccharide chain of Campylobacter fetus serotype B lipopolysaccharide is a D-rhamnan terminated with 3-O-methyl-D-rhamnose (D-acofriose).

An O-specific polysaccharide was liberated from Campylobacter fetus subsp. fetus serotype B lipopolysaccharide by mild acid hydrolysis followed by gel chromatography. This polysaccharide was found to contain D-rhamnose and 3-O-methyl-D-rhamnose (D-Rha3Me, D-acofriose) in a ratio of approximately 24:1, as well as lipopolysaccharide core constituents. The structure of the polysaccharide was studied by 1H-NMR and 13C-NMR spectroscopy, which included two-dimensional COSY, rotating-frame NOE spectroscopy (ROESY), and computer-assisted analysis of the 13C-NMR spectrum. Methylation analysis using [2H3]methyl iodide and Smith degradation followed by GLC/MS of the derived acetylated oligosaccharide-alditols was used to determine the location of D-acofriose. The O-specific polysaccharide is linear, consists on average of 12 disaccharide repeating units, and is terminated by a residue of D-acofriose. The following structure of the D-rhamnan chain was established: [sequence: see text]

Campylobacter fetus↗

Differentiation of the subspecies of Campylobacter fetus by genomic sizing.

Campylobacter fetus subsp. fetus and C. fetus subsp. venerealis are currently differentiated by tolerance to glycine and by their epidemiology. Analysis of C. fetus DNA by pulsed-field gel electrophoresis, after digestion with the restriction endonucleases SmaI and SalI, was used to differentiate between the subspecies. All strains presently identified as C. fetus subsp. fetus had a genomic size of 1.1 Mb, whereas the majority of the C. fetus subsp. venerealis strains had a genomic size of 1.3 Mb. An additional group of strains, which were previously described as C. fetus subsp. venerealis biovar "intermedius" and were able to tolerate higher concentrations of glycine than the rest of the C. fetus subsp. venerealis strains, had an average genome size of 1.5 Mb. We suggest that pulsed-field gel electrophoresis may be useful as an additional aid in the differentiation of C. fetus strains at the subspecies level.

Campylobacter fetus↗