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PubMed · 6784211

Exchanges between plasma and red cells at a variable temperature.

Abstract

When blood temperature is varied in closed ('anaerobic') conditions, the difference between plasma pH and red cell pH stays remarkably constant. Model studies show that this constancy results from diffusive CO2 equilibration and Donnan equilibrium of HCO3- and Cl- ions, more than from a strictly defined buffer composition.

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J L Rodeau, A Malan. 1980. Exchanges between plasma and red cells at a variable temperature.. https://doi.org/10.1016/0034-5687(80)90124-3

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Activity-dependent pH shifts and periodic recurrence of spontaneous interictal spikes in a model of focal epileptogenesis.

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Acid-Base Equilibrium

Use of a handheld device for analysis of blood electrolyte concentrations and blood gas partial pressures in dogs and horses.

OBJECTIVE: To compare, for blood samples from dogs and horses, blood electrolyte concentrations, blood gas partial pressures, and Hct obtained using a handheld analyzer with those obtained using a standard chemistry analyzer and to compare results obtained with the handheld analyzer using warm versus cold test cartridges. DESIGN: Case series with analysis of split samples. SAMPLE POPULATION: Blood samples from 22 dogs and 17 horses. PROCEDURE: Sodium, potassium, ionized calcium, bicarbonate, and total CO2 concentrations, pH, PO2, PCO2, base excess, and Hct were determined by use of a handheld analyzer and test cartridges that had been allowed to warm to ambient temperature or had been recently removed from a refrigerator. Results were compared with those from a standard chemistry analyzer by use of linear regression. RESULTS: For canine samples, values obtained with the handheld analyzer and warm cartridges were highly correlated (r2 > or = 0.83) with values obtained with the standard chemistry analyzer, except for sodium concentration (r2 = 0.6). For equine samples, values obtained with the handheld analyzer and warm cartridges were highly correlated (r2 > or = 0.79) with values obtained with the standard chemistry analyzer, except for Hct (r2 = 0.38). For all samples, results obtained with cold and warm cartridges were moderately correlated (r2 > or = 0.69). CLINICAL IMPLICATIONS: Results obtained with the handheld analyzer were similar to those obtained from the standard chemistry analyzer, with the exception of sodium concentration for canine samples and Hct for equine samples. Results were not substantially affected by use of cold, rather than warm, test cartridges.

Acid-Base Equilibrium