PubMed · 6788668
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H A Kontos. 1981. Intractable syncope.. https://doi.org/10.1080/21548331.1981.11946796
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We describe a case of acquired primary hypothyroidism in a prepubertal girl who presented with profound bradycardia, precocious puberty, and severe vaginal bleeding. A pelvic ultrasound revealed markedly enlarged ovaries with numerous cysts. Cystic aspiration, in concert with L-thyroxine therapy, appeared to halt vaginal bleeding, and led to resolution of cysts. This is the first reported case of percutaneous cyst aspiration to treat ovarian hyperstimulation caused by hypothyroidism in a child.
A number of studies have evaluated the effect of cardiac pacing for prevention of tilt induced vasovagal syncope. The findings are relatively consistent. Pacing does not prevent the onset of vasovagal syncope. This is predictable since hypotension (vasodepressor effect) typically occurs prior to bradycardia. However, dual chamber may prolong the presyncopal period in patients with a prominent cardioinhibitory component. Further, the relation of laboratory observations to spontaneous events is uncertain. In the largest retrospective assessment of pacing efficacy, 89% of patients reported improved symptoms and 62% remained free of symptom recurrence over 50 months.