PubMed · 6829518
Acetaminophen poisoning in infancy.
Abstract
Acetaminophen is widely used in children of all ages, and overdosage from this medication is common. Although severe hepatotoxicity from over-dosage occurs in adults, acetaminophen seems to have a wide margin of safety in younger children. This has been ascribed to altered pharmacokinetics in this age group. We report two cases in which severe acetaminophen-induced hepatoxocity occurred in two infants. Neither infant reportedly received potentially toxic dosages, by history, but toxic drug levels were present in both.
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J W Greene, L Craft, F Ghishan. 1983. Acetaminophen poisoning in infancy.. https://doi.org/10.1001/archpedi.1983.02140300064018
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