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Morphologic and functional tubular changes in chronic glomerulonephritis.

H Klinkmann·M Ratner·V V Serov·H Nizze·B I Rosenfeld·W Sinn·R Schmicker
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Abstract

In 135 patients with different glomerular diseases but normal glomerular filtration rates (CCr and In = 103 +/- 2ml/min) correlations between morphological tubular lesions (tic) and changes in tubular function were investigated. Between the extent of tubular lesions and the impairment of specific tubular functions (formula; see text) exists a highly significant correlation. The combined diminution in Uosmmax and UNH4 + V reflects in 72 per cent the appearance of a severe tubular lesion and should be used for its clinical recognition.

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BiopsyGlomerular Filtration RateGlomerulonephritisHumansKidney Function TestsKidney TubulesTime FactorsJournal Article

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H Klinkmann, M Ratner, V V Serov, H Nizze, B I Rosenfeld, W Sinn, R Schmicker. 1983. Morphologic and functional tubular changes in chronic glomerulonephritis.. https://pubmed.ncbi.nlm.nih.gov/6878260/

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