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PubMed · 6937399

Cellular response to orthodontic force.

W E Roberts·W C Goodwin·S R Heiner
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Abstract

Orthodontic force systems, by way of stress/strain, are transduced to a biologic signal that affects a multifaceted bone remodeling response. Tooth movement involves not only a periodontal ligament response (alveolus translocation), but also bursts of resorption associated with truncated remodeling events in the path of the advancing tooth. Osteoclasts are recruited primarily from the macrophage/monocyte series, whereas osteoblasts are produced by local periodontal ligament cell proliferation and differentiation. Based on nuclear size, periodontal cells are a multicompartmental population. The relatively large nuclei (D fraction) are the immediate precursors of osteoblasts, and the cells with small nuclei (A fraction are apparently the undifferentiated, germinal compartment.

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Alveolar ProcessBone ResorptionHumansOsteoblastsOsteoclastsOsteogenesisPeriodontal LigamentStress, MechanicalTooth Movement TechniquesJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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W E Roberts, W C Goodwin, S R Heiner. 1981. Cellular response to orthodontic force.. https://pubmed.ncbi.nlm.nih.gov/6937399/

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