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PubMed · 7068605

Proteodermatan sulfate isolated from pig skin.

S P Damle·L Cöster·J D Gregory
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Abstract

The major proteoglycan of pig skin, a proteodermatan sulfate, has been isolated under mild conditions in the presence of protease inhibitors. After purification by ion exchange and gel chromatography, it has a Mr of 70 x 10(3) and it does not form aggregates with hyaluronic acid. It contains about 60% protein, one chain of dermatan sulfate, and several oligosaccharide chains. The dermatan sulfate is high in iduronic acid (85% of the uronic acid) and there are no chains of chondroitin sulfate present. The oligosaccharides contain glucosamine, sialic acid, and neutral sugars.

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Amino AcidsAnimalsCarbohydratesChondroitinChromatography, GelChromatography, Ion ExchangeDermatan SulfateMolecular WeightOligosaccharidesProteoglycansSkinSwineJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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S P Damle, L Cöster, J D Gregory. 1982-05-25. Proteodermatan sulfate isolated from pig skin.. https://pubmed.ncbi.nlm.nih.gov/7068605/

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