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PubMed · 7097497

Liquid membrane phenomena in haloperidol action.

S B Bhise·P R Marwadi·S S Mathur·R C Srivastava
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Abstract

Haloperidol, a surface-active neuroleptic drug, was shown to generate a liquid membrane on a supporting membrane. Transport of adrenalin, noradrenalin, dopamine, serotonin, histamine, glutamic acid, gamma-aminobutyric acid, and sodium, potassium, and calcium ions through the haloperidol liquid membrane was studied. The data indicate that the phenomenon of a liquid membrane plays a significant role in the mechanism of action of haloperidol.

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Amino AcidsBiogenic AminesCalciumChemical PhenomenaChemistry, PhysicalHaloperidolMembranes, ArtificialPermeabilityPotassiumSodiumSurface-Active AgentsJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

S B Bhise, P R Marwadi, S S Mathur, R C Srivastava. 1982. Liquid membrane phenomena in haloperidol action.. https://doi.org/10.1002/jps.2600710512

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