Progress toward a potentially implantable, enzyme-based glucose sensor.

D A Gough; J K Leypoldt; J C Armour

doi:10.2337/diacare.5.3.190

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Progress toward a potentially implantable, enzyme-based glucose sensor.

D A Gough·J K Leypoldt·J C Armour

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Abstract

Our efforts toward the development of a potentially implantable, enzyme-based glucose sensor have concentrated on understanding in sufficient detail the most important component, the enzyme-containing membrane. We describe here some features that this membrane must have to operate as a constituent of a chronically implanted sensor. A model of reaction and diffusion within the membrane is outlined and methods of membrane characterization are reviewed.

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Biological Transport Blood Glucose Electrodes, Implanted Enzymes, Immobilized Glucose Membranes, Artificial Models, Chemical Oxygen Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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D A Gough, J K Leypoldt, J C Armour. Progress toward a potentially implantable, enzyme-based glucose sensor.. https://doi.org/10.2337/diacare.5.3.190

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