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PubMed · 7276449

Interactions between intracranial electrical self-stimulation behavior and cardiovascular responses.

L Angyán
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Abstract

Interactions between electrical self-stimulating behavior, cardiovascular state and reactions were studied in a series of chronically prepared cats. Pressor responses were found to be the most common cardiovascular concomitants of intracranial electrical self-stimulating behavior in cats. The lever-pressing rate for brain stimulation decreased under the effect of both dibenzyline, an adrenergic blocking agent, and local anesthesia of the cervical vago-sympathetic trunk by procaine. Bilateral vagotomy resulted in an acceleration in lever-pressing responses. The depression and the acceleration in the lever-pressing for brain stimulation were associated with an increase and a decrease in pulse pressure, respectively. It is suggested that peripheral autonomic modifications exert a regulatory feedback effect on the rewarding property of brain stimulation.

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Adrenergic FibersAnimalsAutonomic Nervous SystemBrainCardiovascular SystemCatsElectric StimulationFemaleHemodynamicsMaleRespirationSelf StimulationVagus NerveJournal Article

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BibTeXRIS

L Angyán. 1981. Interactions between intracranial electrical self-stimulation behavior and cardiovascular responses.. https://doi.org/10.1016/0165-1838(81)90094-1

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