PubMed · 7282113
[Drug-induced fluorosis].
Abstract
Report of a 58 year old patient who, after a 5 year continuous treatment with altogether 146 g sodium fluoride, developed a grade II-III (Roholm) fluorosis. The fluorine treatment had been conducted for a radiologically demonstrated osteoporosis. Renal involvement was not demonstrated: serum creatinine was normal, the creatinine clearance only slightly reduced. The therapeutic goal of this continuous fluoride administration, i.e. freedom from skeletal pain and vertebral stability, was not achieved; new end plate impressions of dorsal vertebrae were found.
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G Strohmeyer, M Bunata. [Drug-induced fluorosis].. https://pubmed.ncbi.nlm.nih.gov/7282113/
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