Evolution and longevity-assurance processes.

R W Hart; A Turturro

doi:10.1007/bf00401663

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Evolution and longevity-assurance processes.

R W Hart·A Turturro

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Abstract

The role of the development of information fidelity systems in evolution is explored, with evidence that the loss in the ability to maintain the integrity of homeostasis in organisms over time, aging, is correlated with the loss in the ability to maintain integrity at the molecular biological level. Evolutionary-comparative analysis places an upper limit on the number of these systems important to the evolution of longevity in the primates, and suggests the importance of insuring the stability of information bearing macromolecules in evolution and the role of modulators of damage to these moieties in the expression of the senescent state.

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Aging Animals Biological Evolution DNA Replication Dogs Genes Longevity Mice Neoplasms Rats Risk Species Specificity Comparative Study Journal Article

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R W Hart, A Turturro. 1981. Evolution and longevity-assurance processes.. https://doi.org/10.1007/bf00401663

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