Catch-up growth.

J P Williams

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PubMed · 7334313

Catch-up growth.

J P Williams

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Abstract

Catch-up growth, defined as growth velocity above the statistical limits of normality for age or maturity during a defined period of time, is distinguished from compensatory growth since it makes up for a potential loss rather than an actual loss and is seen in the whole body as opposed to specific organs. The cellular explanation for catch-up based on the work of Winick is described and a recent challenge to this explanation is briefly discussed. The mechanism of mismatch between actual size and 'planned' size suggested by Tanner is described and tested. In a series of experiments conducted in rats of different ages the degree of mismatch and the role of catch-up are compared for two different parameters, body weight and nose-rump length. It was found that the two parameters behaved differently and it is suggested that while the concept of mismatch is still acceptable the idea of a single central mechanism is not supported. It is suggested that the mismatch mechanism is a cellular phenomenon.

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Aging Animals Animals, Suckling Biometry Body Weight Cell Division Female Food Deprivation Growth Kinetics Male Rats Sex Factors Comparative Study Journal Article Research Support, Non-U.S. Gov't

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J P Williams. 1981. Catch-up growth.. https://pubmed.ncbi.nlm.nih.gov/7334313/

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