[Factor analysis of immunogenetic data].

M S Eppel'

PubMed · 7335081

[Factor analysis of immunogenetic data].

Abstract

The author proposes a method for analysing the immunogenetic tables containing data on antigen series typed by the antiserum series. The method proposed admits the presence of both complex antigens possessing different sites and non-monospecific serum. This is essential for the analysis of such polymorphic systems as major histocompatibility. The method enables one to determine the class of the main sites (factors) describing the majority of the typing data. The method and the criterion for the evaluation of the statistical significance of the results obtained is actualized in a FORTRAN-IV programme. The programme was used for analysing the data on H-linked genes controlling immune responsiveness. The results are in good accordance with the contemporary conceptions on the Ir-genes system.

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Animals Computers Immunogenetics Major Histocompatibility Complex Mathematics Proteins English Abstract Journal Article

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M S Eppel'. [Factor analysis of immunogenetic data].. https://pubmed.ncbi.nlm.nih.gov/7335081/

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