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PubMed · 7358821

Isocratic multi-column high-performance liquid chromatography as a technique for qualitative analysis and its application to the characterisation of basic drugs using an aqueous methanol solvent.

B B Wheals
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Abstract

A variety of high-performance liquid chromatography packing materials were prepared and their chromatographic properties compared for separating several basic drugs using a single solvent system. The three most promising packing materials (silica, a mercapto propyl modified silica and a n-propyl sulphonic acid modification) were subsequently used to provide retention volume data for a large number of drugs.

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Chromatography, High Pressure LiquidHydrogen-Ion ConcentrationMethanolPharmaceutical PreparationsSolventsStructure-Activity RelationshipJournal Article

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B B Wheals. 1980-01-04. Isocratic multi-column high-performance liquid chromatography as a technique for qualitative analysis and its application to the characterisation of basic drugs using an aqueous methanol solvent.. https://doi.org/10.1016/s0021-9673(00)87874-7

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