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PubMed · 740684

Does long term haemofiltration provoke secondary hyperparathyroidism?

H Schneider·E Streicher·H Schmidt-Gayk·S Bosnjakovic
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Abstract

One thousand nine hundred and forty-nine haemofiltration procedures have been performed since 1976; 4 different types of haemofilters have been tested in gravimetric and volumetric haemofiltration machines. Balance studies revealed a diminished calcium intake of about 1/3 of that found in conventional dialysis. Magnesium balance is negative and leads to decreasing serum Mg values. Inorganic phosphate is removed in similar quantity to dialysis. PTH levels increase during 3--18 months of treatment, whereas 25-OH-D3 levels rapidly fell, gc-globulin- and HCT-levels did not change markedly. g-c globulin could be detected in filtrate samples in remarkable amounts, 25-OH-D3 was found in traces. Radiologically no apparent alteration occurred. We recommend Vitamin D supplementation to compensate for the losses and thereby avoid development of secondary hyperparathyroidism.

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CalciumHumansHyperparathyroidism, SecondaryMagnesiumPhosphatesRenal DialysisUltrafiltrationVitamin DJournal Article

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H Schneider, E Streicher, H Schmidt-Gayk, S Bosnjakovic. 1978. Does long term haemofiltration provoke secondary hyperparathyroidism?. https://pubmed.ncbi.nlm.nih.gov/740684/

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