[Haptoglobin types and chronic glomerulonephritis].

Abstract

In 88 patients a chronic glomerulonephritis was diagnosed by histology and immunohistology. The haptoglobin type was also analyzed. The distribution of the haptoglobin types in the sample did not differ from the haptoglobin distribution in the population of Berlin. The distributions of histologic and immunohistologic forms of glomerulonephritis were related to the haptoglobin distribution in our patients. The distribution of histological subgroups does not depend on the distribution of the haptoglobins. In evaluation of the immunohistological subgroups we found that immunocomplexnephritis is less frequent in the group Hp 1--1 than in the groups 2--1 and 2--2. We suppose that persons with Hp 2--1 and Hp 2--2 are prone to increased antibody formation. Hp 1--1 is presumably a blocking antibody.