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PubMed · 7458393

Neonatal rickets. Histopathology and quantitative bone changes.

S J Oppenheimer·G J Snodgrass
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Abstract

Ribs from 3 preterm infants, who had died after prolonged intravenous feeding and artificial ventilation, were examined histologically and assessed for the degree of osteomalacia and osteoporosis in cancellous bone of the shaft. A grid counting technique was used. Osteomalacia was noted in all 3 cases but to a lesser degree than in classical vitamin D-deficient controls. Osteoporosis was pronounced in the cases of neonatal rickets, but this was not a feature of the vitamin D-deficient controls. Histological features were similar to those reported in experimental phosphate-deficient rickets and vitamin D-resistant rickets.

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Bone and BonesHumansInfant, NewbornInfant, Newborn, DiseasesOsteomalaciaOsteoporosisRicketsCase ReportsComparative StudyJournal Article

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S J Oppenheimer, G J Snodgrass. 1980. Neonatal rickets. Histopathology and quantitative bone changes.. https://doi.org/10.1136/adc.55.12.945

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