PubMed HealthSearch

PubMed · 7461508

[Reflections on epileptic personality changes].

Abstract

When epileptic seizures occur suddenly in puberty, the patient is seized with the feeling of anxiety, isolation and despair, and this feeling is increased by the special quality of puberty. The patient tries to overcome this critical situation by including "epilepsy" in his own personality. When this process is accomplished in puberty in which an ego-identification is done, an epileptic personality disorder is formed gradually. Accordingly, how the patient tides over this crisis is important for the formation of an epileptic personality disorder. In order to prevent the development of this condition, it is necessary to apply psychotherapy.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

T Date. 1980. [Reflections on epileptic personality changes].. https://pubmed.ncbi.nlm.nih.gov/7461508/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Long-term seizure outcomes and factors associated with response to adjunctive everolimus in TSC-associated epilepsy.

BACKGROUND: Everolimus, a mechanistic target of rapamycin (mTOR) inhibitor, is increasingly used in tuberous sclerosis complex (TSC)-associated epilepsy; however, long-term real-world outcomes and factors associated with favorable response remain unclear. This study aimed to evaluate the long-term seizure outcomes of adjunctive everolimus and explore clinical factors associated with treatment response. METHODS: We retrospectively recruited 21 patients with active TSC-associated epilepsy receiving adjunctive everolimus and assessed seizure outcomes during follow-up. Clinical characteristics were compared between responders and non-responders at 1 year after treatment initiation. RESULTS: Over a median treatment duration of 72 months, responder rates ranged from 53.8% to 64.7%, and seizure-free rates ranged from 33.3% to 41.2%. Responders had fewer involved organ systems at baseline (median 3 vs. 4, p = 0.020) and lower anti-seizure medication burden (median 2 vs. 4, p = 0.045). Younger age at treatment initiation showed a trend toward improved response. CONCLUSION: Adjunctive everolimus was associated with sustained long-term seizure reduction in this real-world cohort. In exploratory analyses, fewer involved organ systems and fewer baseline ASMs were associated with favorable treatment response. These findings require validation in larger prospective cohorts.

Epilepsy