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PubMed · 747383

[Thyroid secretion in experimental hyperplasia (author's transl)].

P Nève·P Rocmans·P Ketelbant-Balasse·J E Dumont
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Abstract

Hyperactive dog thyroids were prepared by repeated TSH stimulation in vivo. Butanol extractable 125iodine (BE 125I) release in vitro from such hyperactive thyroid slices was enhanced when compared with resting slices. Apical pseudopods an colloid droplets were exceptional in such hyperactive thyroids. Moreover, BE125I release was intensitive to cytochalasin B, microtubules and metabolic inhibitors, and decreased only with temperature. Our data demonstrate that hormonal secretion by hyperactive thyroids is not secondary to apical phagocytosis of colloid droplets.

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AnimalsCytochalasin BDogsHyperthyroidismIn Vitro TechniquesIodine RadioisotopesTemperatureThyroid GlandThyrotropinEnglish AbstractJournal Article

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P Nève, P Rocmans, P Ketelbant-Balasse, J E Dumont. 1978. [Thyroid secretion in experimental hyperplasia (author's transl)].. https://pubmed.ncbi.nlm.nih.gov/747383/

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