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PubMed · 752134

Evolution of a genetic code simulated with the computer.

H Kuhn·C Kuhn
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Abstract

A simple selforganizing model system of molecules is considered and it is demonstrated by a computer simulation, that a genetic code of 16 elements (aminoacids) can gradually be formed by such a system in the course of many generations. By a number of rare chance events, each suppressing other events of equal a priori probability, a single code results out of an immense number of possible codes of the same a priori probability. The result is discussed in relation to the uniqueness of the genetic code in living systems. The computer simulation emphasizes a particular step in a model pathway discussed elsewhere consisting of many assumed physicochemical steps leading to a genetic apparatus.

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Base SequenceBiological EvolutionComputersGenetic CodeModels, BiologicalPurinesPyrimidinesJournal Article

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H Kuhn, C Kuhn. 1978. Evolution of a genetic code simulated with the computer.. https://doi.org/10.1007/bf00931411

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