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Ptosis after blepharoplasty.

Abstract

Ptosis is a complication that can arise after blepharoplasty resulting in lid asymmetry. It should be recognized early and intervention directed at its underlying anatomical cause. Ptosis can be secondary to lid edema, hematoma, septal levator adhesions, septal suturing, supratarsal fixation, and levator complex injury. Injury to the levator complex can be rarefaction, dehiscence, or disinsertion. Evaluation of this condition involves assessment of the degree of ptosis and the amount of levator function. Severe ptosis with poor levator function requires reexploration and repair of the levator mechanism. Mild or moderate ptosis may resolve spontaneously and can be managed expectantly. Chronic cases (longer than 3 months) may need exploration, and the procedure used is guided by the amount of levator function present.

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BibTeXRIS

F G Wolfort, J V Poblete. 1995. Ptosis after blepharoplasty.. https://doi.org/10.1097/00000637-199503000-00007

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Identification of a novel mutation in a Korean patient with oculopharyngeal muscular dystrophy.

Oculopharyngeal muscular dystrophy (OPMD) is a late-onset muscle disorder characterized by progressive dysphagia and bilateral ptosis. Mutations in the polyadenylate binding protein nuclear 1 (PABPN1) gene have been found to cause OPMD. The typical mutation is a stable trinucleotide repeat expansion in the first exon of the PABPN1 gene, in which (GCG)(6) is the normal repeat length. We investigated a Korean patient with OPMD and identified a novel mutation: a heterozygous insertion of a 9-bp sequence [(GCG)(GCA)(GCA); c.27_28insGCGGCAGCA] instead of the (GCG) repeat expansion, resulting in an in-frame insertion of three alanines (p.A10insAAA). To the best of our knowledge, this is the first report of a genetically confirmed case of OPMD in Korea.

Blepharoptosis↗