PubMed · 7613341
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T Walley. 1995-07-01. Upper gastrointestinal endoscopy.. https://doi.org/10.1136/bmj.311.6996.57c
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The AIDS Community Demonstration Projects (ACDPs) were community-level human immunodeficiency virus-prevention programs targeting high-risk populations in five U.S. cities. For the intervention design, researchers developed a common study protocol based on behavior-change theories and models. This report describes the common study protocol used in the ACDPs, the preliminary findings, and the conclusions regarding the design, implementation, and evaluation of a community-level intervention; specific case studies from each project site are also described.
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Extensive long segment resection for carcinoma of the esophagus including also consequent mediastinal and celiac lymph node dissection is able to achieve satisfactory radicality only in early tumor stages while there is little influence on long term prognosis for advanced tumor stages. Only better risk analyses and improved surgical outcome with reduced operative mortality has improved the overall outcome. In locally limited primary tumors and even more in locally advanced stages generalisation or dissemination of tumor disease is to be expected. Therefore it is generally agreed upon that only multimodal therapy including systemic chemotherapy and local radiotherapy is able to improve therapeutic results in this disease with otherwise very poor prognosis. We report our own experience on 200 esophageal resections including modification of our strategy and protocol presently in use for tumor stages IIB to IV.