PubMed HealthSearch

PubMed · 7617428

Optic flow and autonomous navigation.

Abstract

Many animals, especially insects, compute and use optic flow to control their motion direction and to avoid obstacles. Recent advances in computer vision have shown that an adequate optic flow can be computed from image sequences. Therefore studying whether artificial systems, such as robots, can use optic flow for similar purposes is of particular interest. Experiments are reviewed that suggest the possible use of optic flow for the navigation of a robot moving in indoor and outdoor environments. The optic flow is used to detect and localise obstacles in indoor scenes, such as corridors, offices, and laboratories. These routines are based on the computation of a reduced optic flow. The robot is usually able to avoid large obstacles such as a chair or a person. The avoidance performances of the proposed algorithm critically depend on the optomotor reaction of the robot. The optic flow can be used to understand the ego-motion in outdoor scenes, that is, to obtain information on the absolute velocity of the moving vehicle and to detect the presence of other moving objects. A critical step is the correction of the optic flow for shocks and vibrations present during image acquisition. The results obtained suggest that optic flow can be successfully used by biological and artificial systems to control their navigation. Moreover, both systems require fast and accurate optomotor reactions and need to compensate for the instability of the viewed world.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M Campani, A Giachetti, V Torre. 1995. Optic flow and autonomous navigation.. https://doi.org/10.1068/p240253

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Generating correlated data for omics simulation.

Simulation of realistic omics data is a key input for benchmarking studies that help users obtain optimal computational pipelines. Omics data involves large numbers of measured features on each sample and these measures are generally correlated with each other. However, simulation too often ignores these correlations, perhaps due to computational and statistical hurdles of doing so. To alleviate this, we describe three approaches for generating omics-scale data with correlated measures which mimic real datasets. These approaches are all based on a Gaussian copula approach with a covariance matrix that decomposes into a diagonal part and a low-rank part. This decomposition allows for extremely efficient simulation, overcoming a hurdle for adoption of past methods. We use these approaches to demonstrate the importance of including correlation in two benchmarking applications. First, we show that variance of results from the popular DESeq2 method increases when dependence is included. Second, we demonstrate that CYCLOPS, a method for inferring circadian time of collection from transcriptomics, improves in performance when given gene-gene dependencies in some circumstances. We provide an R package, dependentsimr, that has efficient implementations of these methods and can generate dependent data with arbitrary marginal distributions, including discrete (binary, ordered categorical, Poisson, negative binomial), continuous (normal), or with an empirical distribution.

Computer Simulation

Addressing current challenges in cancer immunotherapy with mathematical and computational modelling.

The goal of cancer immunotherapy is to boost a patient's immune response to a tumour. Yet, the design of an effective immunotherapy is complicated by various factors, including a potentially immunosuppressive tumour microenvironment, immune-modulating effects of conventional treatments and therapy-related toxicities. These complexities can be incorporated into mathematical and computational models of cancer immunotherapy that can then be used to aid in rational therapy design. In this review, we survey modelling approaches under the umbrella of the major challenges facing immunotherapy development, which encompass tumour classification, optimal treatment scheduling and combination therapy design. Although overlapping, each challenge has presented unique opportunities for modellers to make contributions using analytical and numerical analysis of model outcomes, as well as optimization algorithms. We discuss several examples of models that have grown in complexity as more biological information has become available, showcasing how model development is a dynamic process interlinked with the rapid advances in tumour-immune biology. We conclude the review with recommendations for modellers both with respect to methodology and biological direction that might help keep modellers at the forefront of cancer immunotherapy development.

Computer Simulation