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PubMed · 7654672

[Glaucomatous optic neuropathy].

Abstract

The pathogenic mechanisms of the glaucomatous optical neuropathy in the open angle glaucoma are incompletely elucidated, being a subject of current research. The alteration of the optic nerve in glaucoma reveals either an ischaemic cause, either a mechanical compression; other theories imply the alteration of the axo-plasmic flow, or freeing of some X-hystothonical substances, or the initial alteration of the lamina criblata. Modern examination of the optical disk in glaucoma, using computer-aided planimetry methods and papillary circulation studying by Doppler laser velocimetry, fluorescein angiography a.s.o., is not part of the current practice of examination. Yet, it is extensively used in scientific research, for revealing of new physiopathological aspects.

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BibTeXRIS

C Mocanu. [Glaucomatous optic neuropathy].. https://pubmed.ncbi.nlm.nih.gov/7654672/

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Increased disk size in glaucomatous eyes vs normal eyes in the Reykjavik eye study.

PURPOSE: To evaluate the use of disk diameter as an indicator in the identification of glaucomatous optic neuropathy. METHODS: We evaluated all available stereofundus photographs for 1,040 right eyes obtained in the Reykjavik Eye Study. Horizontal and vertical disk diameters were determined in a masked manner by a glaucoma specialist (K.F.D.). All disk diameters were corrected for refractive error. RESULTS: There were significant differences (P <.05) between the corrected vertical disk diameters of normal subjects (0.189 +/- 0.018 inches) and those suspected of having glaucoma (0.202 +/- 0.020 inches) as well as between the normal and the glaucoma groups (0.206 +/- 0.029 inches). The corrected horizontal measurement showed the same pattern. CONCLUSIONS: In the Reykjavik Eye Study, optic disks meeting structural criteria for glaucoma are significantly larger than normal nerves.

Glaucoma, Open-Angle↗