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PubMed · 7667854

[Infantile colic--what will help?].

Abstract

Infantile colic occurs in 1/3 of all infants and is still a medical mystery. This paper reviews the etiology and the documented therapies. The overall aim is to avoid that inefficient forms of medication are used for this indication. It is not yet known whether colic is a dysfunction related to physical pain or behaviour. The results from 885 infants born in Oslo suggested that colic was frequent among those whose mothers both breastfed them and smoked more than five cigarettes daily. No increase in relative risk was found for other maternal or demographic factors. Since it is impossible to treat the causes parents should be advised to try general and specific strategies. General advice includes support, interest and care from health personnel and assistance from relatives. Specifically, some infants respond to either dietary changes (no cow's milk), oral sucrose infusion, vibro-accustic treatment, behavioural therapy or carrying, but avoiding hyperstimulation. Nicotine-free breast milk has not been evaluated. The available pharmacotherapy is not efficacious. Alternative medicine (herbal teas, chiropractic, acupuncture), has not yet been proven to be efficacious.

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BibTeXRIS

I Matheson. 1995-08-20. [Infantile colic--what will help?].. https://pubmed.ncbi.nlm.nih.gov/7667854/

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Reduction of crying episodes owing to infantile colic: A randomized controlled study on the efficacy of a new infant formula.

OBJECTIVES: The aim of this study was to evaluate the efficacy on crying episodes owing to infantile colic of a new infant formula containing partially hydrolysed whey proteins, prebiotic oligosaccharides (OS), with a high beta-palmitic acid content. DESIGN: Prospective randomized controlled study. SETTING: Italy. SUBJECTS: Two hundred and sixty-seven formula-fed infants, aged less than 4 months, with infantile colic, were randomized to receive either the new infant formula (study treatment (ST)) or a standard formula and simethicone (6 mg/kg twice a day) (control treatment (CT)). A questionnaire was given to parents to evaluate for 14 days the daily number of colic episodes and crying time. RESULTS: Out of the 199 infants who completed the study, 96 were treated with the new formula and 103 were not treated. Infants receiving the new formula had a significant decrease in colic episodes after 1 week (2.47+/-1.94 at day 7 vs 5.99+/-1.84 at the study entry) compared to infants receiving the CT (3.72+/-1.98 at day 7 vs 5.41+/-1.88 at the study entry) (P < 0.0001). Also at day 14, the crying episodes were significantly different between the two groups of infants (1.76+/-1.60 in ST vs 3.32+/-2.06 in CT) (P < 0.0001). CONCLUSIONS: The use of a partially hydrolysed formula supplemented with fructo- and galacto-OS induces a reduction of crying episodes in infants with colic after 7 and 14 days when compared with a standard formula and simethicone.

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