Canine distemper virus and multiple sclerosis.

S Krakowka; A Koestner

doi:10.1016/s0140-6736(78)90302-1

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Canine distemper virus and multiple sclerosis.

S Krakowka·A Koestner

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Abstract

Serum samples from patients with multiple sclerosis (M.S.), patients with subacute sclerosing panencephalitis (S.S.P.E.), and controls were examined for virus-neutralising antibodies against measles virus (M.V.) and 2 strains of canine distemper virus (C.D.V.). M.S. and S.S.P.E. patients had higher M.V. antibody titres than controls. In contrast, no significant differences were observed in mean C.D.V.-neutralising antibody titres between M.S. patients and controls. The results, though obtained from a small number of patients, fail to implicate C.D.V. in the aetiology of M.S.

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Animals Antibodies, Viral Disease Vectors Distemper Distemper Virus, Canine Dogs Humans Measles virus Multiple Sclerosis Neutralization Tests Subacute Sclerosing Panencephalitis Zoonoses Journal Article Research Support, U.S. Gov't, P.H.S.

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S Krakowka, A Koestner. 1978-05-27. Canine distemper virus and multiple sclerosis.. https://doi.org/10.1016/s0140-6736(78)90302-1

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