Can immobilization be exploited to modify enzyme activity?

D S Clark

doi:10.1016/0167-7799(94)90018-3

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Can immobilization be exploited to modify enzyme activity?

D S Clark

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Abstract

Immobilization has long been recognized as a useful tool for retaining enzymes in bioreactors and enabling the continuous operation of enzymic processes. However, the potential of immobilization for modifying enzyme activity in an advantageous, if not predictable, manner is less-well appreciated. This review summarizes selected studies that have used immobilization to tailor the catalytic properties of enzymes, and highlights the application of immobilization to the rational design of biocatalysts.

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Alcohol Dehydrogenase Animals Biotechnology Catalysis Chymotrypsin Computer Graphics Drug Design Enzymes, Immobilized Horses Kinetics Models, Molecular Serine Endopeptidases Solutions Structure-Activity Relationship Water beta-Galactosidase Journal Article Review

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D S Clark. 1994. Can immobilization be exploited to modify enzyme activity?. https://doi.org/10.1016/0167-7799(94)90018-3

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