PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 7767016

Corneal vascularization.

B E Caffery·J E Josephson
View original source ↗Export metadata ↓

Abstract

Corneal vascularization is an important clinical event that requires careful management. Vessel penetration can serve to heal a threatening inflammatory process, cause opacification and loss of vision, induce graft rejection, or serve as a warning of corneal distress. The latter condition is particularly common in contact lens wearers. Practitioners should be aware of the subtle signs of early neovascularization, and work toward its remission. Acute vessel penetration is a difficult clinical situation to manage. Quiescent vessels in the cornea must be explained by history and managed with either monitoring or intervention.

Explore related subjects

Contact LensesCorneaCorneal NeovascularizationHumansRisk FactorsJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

B E Caffery, J E Josephson. 1995. Corneal vascularization.. https://pubmed.ncbi.nlm.nih.gov/7767016/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1996

Optic disc height measurement with the Zeiss 4-mirror contact lens and 78 dioptre lens compared.

Measurements of optic disc diameter with the Zeiss 4-mirror contact lens and 78 dioptre (D) lens, made by projecting a slit-beam of known height onto the image of the disc, were compared with planimetric measurements in 30 eyes. The 78 D lens measurements were significantly larger than both the Zeiss lens and planimetric measurements (p < 0.0001 and p = 0.0047 respectively). The measurements using the Zeiss lens and planimetry did not differ significantly. Compared with planimetry, for the 24 eyes within 3 D of emmetropia, the correlation was greater for the Zeiss (r = 0.8591) than for the 78 D lens (r = 0.7148). The Zeiss lens also showed better agreement and less scatter of results compared with the 78 D lens (standard error of the mean +/- 0.0373 mm for the Zeiss and +/- 0.0418 mm for the 78 D lens). The Zeiss contact lens measurements of optic disc diameter show stronger correlation and better agreement with planimetry than measurements using a 78 D lens.

Contact Lenses↗
PubMed1996

[Contact glass tonometer].

BACKGROUND: This paper presents a tonometer built into a contactlens, which allows to measure the eye-pressure and to perform ophthalmoscopy at the same time. Artificially induced changes of the eye-pressure and their influence on the visible fundus can now be checked simultaneously. The contactlens-tonometer (CGT) also is able to record continuously the pulse-curve, which can indicate any circulatory problem. So, the device is expected to give us additional diagnostic criteria of early glaucoma. Each ophthalmologyst in the field will be able to perform with this device a oculodynamometry in an easy way. By this it is possible to estimate the pressure-tolerance of the optic disk from glaucoma-patients. MEASUREMENTS: There have been taken some measurements on enucleated human eyes, comparing our device with a Statham-transducer in the vitreous. We found a good correlation. In a second step, we made measurements (65) on healthy volunteers, comparing the device with Perkins-Tonometry. RESULTS AND CONCLUSIONS: We found a correlation (R = 0.58). The error of the measurements was about +/- 3 mm Hg. Considering both, the deviation of the Perkins-Tonometer with which our results were compared, and the fact of a good correlation (R = 0.999) in the study with the enucleated human eyes, we found that the contact-lens-tonometer measures the intraocular pressure exactly. In future studies, we want to analyze the dynamic component of the measurements.

Contact Lenses↗
PubMed1996

Risk of infection from sleeping with contact lenses on: causes of risk.

Although the risks associated with extended wear contact lenses are well-known, there has not been an adequate explanation of why sleeping with the lenses on increases the risk of infection. It is contended that the reduction in the available oxygen caused by contact lenses does not in itself explain the high rate of corneal infection caused by wearing the lenses while sleeping. This paper examines the contribution that the mechanism of sleep itself makes to the risk of infection, based on patient studies in two optometric practices. The results show that the risk of ocular infection, particularly corneal ulcers, is substantially increased with overnight wear of lenses. A review of the role of oxygen deprivation, atmospheric pollution, bacterial survival strategies, infection-resistant defenses during wakefulness, and patterns of sleep indicates that oxygen deprivation of the cornea is not the only factor in the increased risk associated with wearing the lenses while sleeping. It is suggested that the combination of the introduction of airborne pollutants to the contact lens during the day, the reduced oxygen transmission through contact lenses and closed lids, and the lack of eye and lid movement during sleep together create the conditions in which bacterial infection is most likely to occur.

Contact Lenses↗