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PubMed · 7784558

Breast MR imaging with commercially available techniques: radiologic-pathologic correlation.

E S Fobben·C Z Rubin·L Kalisher·A G Dembner·M H Seltzer·E J Santoro
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Abstract

PURPOSE: To evaluate the clinical utility of dynamic gadolinium-enhanced magnetic resonance (MR) imaging of the breast with commercially available techniques in patients scheduled for excisional biopsy. MATERIALS AND METHODS: A total of 91 breast abnormalities, 70 benign and 21 malignant, were evaluated. Thin-section three-dimensional gradient-echo images were obtained before and 2, 4, and 7 minutes after injection of contrast material. Three radiologists prospectively evaluated the mammograms and MR images. RESULTS: The areas under the receiver operating characteristic curves were 0.820 for mammography and 0.893 for MR imaging (P = .67). Sensitivity of MR imaging was 82.5%, compared with 74.6% for mammography. Specificity of MR imaging was 82.5%, compared with 79.1% for mammography. Enhancement profiles showed early intense enhancement in malignancies but considerable overlap with enhancement of benign disease. CONCLUSION: Breast MR imaging is a slightly more sensitive modality than mammography but not a highly specific technique for evaluating breast lesions. It has utility in several clinical situations but should not be used as a substitute for biopsy or general screening.

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AdultBiopsyBreastBreast DiseasesCarcinomaCarcinoma in SituContrast MediaFemaleFibroadenomaFibrocystic Breast DiseaseGadolinium DTPAHumansMagnetic Resonance ImagingMammographyMiddle AgedOrganometallic CompoundsPentetic AcidProspective StudiesROC CurveSensitivity and SpecificityJournal ArticleResearch Support, Non-U.S. Gov't

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E S Fobben, C Z Rubin, L Kalisher, A G Dembner, M H Seltzer, E J Santoro. 1995. Breast MR imaging with commercially available techniques: radiologic-pathologic correlation.. https://doi.org/10.1148/radiology.196.1.7784558

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