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PubMed · 7922188

Kinins as vasoactive peptides.

W R Fitzgibbon·D W Ploth·H S Margolius
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Abstract

During the past year, a number of significant publications have provided data that clearly establish the basis for the important role of the tissue kallikrein-kinin system in cardiovascular control and renal function. These publications include a report of advances in techniques for system component measurement, reports of the localization of central bradykinin receptors and an alteration in the sensitivity of the central bradykinin system in hypertension, and a description of the effects of new kinin receptor antagonists on our understanding of endogenous and exogenous kinin-induced vasorelaxation and its possible alteration in hypertension. Several significant reports describe the potentiation of endogenous kinin action by kininase inhibitors and establish the important interaction between kininase activity and kinin control of blood pressure.

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Amino Acid SequenceAnimalsCardiovascular Physiological PhenomenaHumansKidneyKininsMolecular Sequence DataPeptidesRenal CirculationJournal ArticleReview

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W R Fitzgibbon, D W Ploth, H S Margolius. 1993. Kinins as vasoactive peptides.. https://doi.org/10.1097/00041552-199303000-00016

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