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PubMed · 7944843

Smoking as a risk factor for sleep-disordered breathing.

D W Wetter·T B Young·T R Bidwell·M S Badr·M Palta
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Abstract

BACKGROUND: Recent evidence indicates that the prevalence of sleep-disordered breathing is remarkably high (24% for men and 9% for women) and that the public health burden attributable to sleep-disordered breathing is substantial. This investigation examines current and former cigarette smoking as potential risk factors for sleep-disordered breathing. METHODS: Data were from 811 adults enrolled in the University of Wisconsin Sleep Cohort Study, Madison. The Sleep Cohort Study is a longitudinal, epidemiologic study that uses nocturnal polysomnography to investigate sleep-disordered breathing and other disorders of sleep. The presence and severity of sleep-disordered breathing was quantified by the frequency of apneas and hypopneas per hour of sleep. RESULTS: Logistic regression analyses were used to control for potential confounding factors. Compared with never smokers, current smokers had a significantly greater risk of snoring (odds ratio, 2.29) and of moderate or worse sleep-disordered breathing (odds ratio, 4.44). Heavy smokers (> or = 40 cigarettes per day) had the greatest risk of mild sleep-disordered breathing (odds ratio, 6.74) and of moderate or worse sleep-disordered breathing (odds ratio, 40.47). Former smoking was unrelated to snoring and sleep-disordered breathing after adjustment for confounders. CONCLUSIONS: Current cigarette smokers are at greater risk for sleep-disordered breathing than are never smokers. Heavy smokers have the greatest risk while former smokers are not at increased risk for sleep-disordered breathing. Thus, smoking cessation should be considered in the treatment and prevention of sleep-disordered breathing.

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AdultConfidence IntervalsConfounding Factors, EpidemiologicFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedOdds RatioPolysomnographyPopulation SurveillancePrevalenceRisk FactorsSeverity of Illness IndexSleep Apnea SyndromesSmokingSmoking PreventionWisconsinJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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D W Wetter, T B Young, T R Bidwell, M S Badr, M Palta. 1994-10-10. Smoking as a risk factor for sleep-disordered breathing.. https://pubmed.ncbi.nlm.nih.gov/7944843/

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