[Pathomorphologic changes in experimental siderosis].

M K Nazaretian; L K Aĭbazian

PubMed · 7980042

[Pathomorphologic changes in experimental siderosis].

Abstract

Experimental hypersiderosis was induced in rabbits by intravenous injection of iron-containing preparation Ferrum Leck. The resultant pronounced hemosiderosis was found in the liver, kidneys, heart, lungs and spleen. Dystrophic and necrotic processes arose in the liver, kidneys, heart. Accumulation of hemosiderin in the vascular walls led to their higher permeability, edema, wall thickness, proliferative changes, especially in the coronary vessels. Intravascular circulation impairment was evident from compression of microvessels by siderophages, red cells aggregation, formation of microthrombi.

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Animals Capillary Permeability Cell Division Coronary Vessels Endothelium, Vascular Hemosiderin Kidney Liver Lung Male Myocardium Necrosis Rabbits Siderosis Spleen Viscera English Abstract Journal Article

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M K Nazaretian, L K Aĭbazian. [Pathomorphologic changes in experimental siderosis].. https://pubmed.ncbi.nlm.nih.gov/7980042/

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