Directed cell movement in pulsed electric fields.

K Franke; H Gruler

PubMed · 8018255

Directed cell movement in pulsed electric fields.

Abstract

Human granulocytes exposed to pulsed electric guiding fields were investigated. The trajectories were determined from digitized pictures (phase contrast). The basic results are: (i) No directed response was induced by pulsed electric guiding fields having a zero averaged field. (ii) A directed response was induced by pulsed electric guiding fields having a non-zero averaged field. (iii) The directed response was enhanced for pulse sequences having a repetition time of 8 s. (iv) The lag-time between signal recognition and cellular response was 8-10 s. The results are discussed in the framework of a self-ignition model.

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Capillary Action Chemotaxis, Leukocyte Electric Stimulation Granulocytes In Vitro Techniques Mathematics Models, Biological Time Factors Journal Article Research Support, Non-U.S. Gov't

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K Franke, H Gruler. Directed cell movement in pulsed electric fields.. https://pubmed.ncbi.nlm.nih.gov/8018255/

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