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PubMed · 812196

Studies on PIVKA-X.

G Gaudernack·H Prydz
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Abstract

The incorporation of 14C-glucosamine and 3H-leucine into PIVKA-X and factor X has been studied in Macaca mulatta by means of a monospecific precipitating antiserum. No difference in the incorporation into PIVKA-X and factor X was found. The half-lives of PIVKA-X and factor X were similar (about 30-35 h and 27-31 h respectively) indicating that the vitamin K-induced modifications did not alter the survival of protein. A Russell's-viper venom/cephalin test system for factor X was more sensitive to inhibition by PIVKA-X than was a tissue thromboplastin-based system.

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AdsorptionAnimalsBarium SulfateDrug StabilityFactor XGlucosamineHalf-LifeHaplorhiniLeucineMacaca mulattaPhosphatidylethanolaminesProtein PrecursorsVitamin KVitamin K DeficiencyWarfarinJournal Article

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G Gaudernack, H Prydz. 1975-11-15. Studies on PIVKA-X.. https://pubmed.ncbi.nlm.nih.gov/812196/

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