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PubMed · 814526

[Austrian complex-study on dipropylacetate. Pediatric experiences].

Ch Groh·F W Rosenmayr
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Abstract

The clinical trial of Dipropylacetat (Convulex) demonstrates the advantages of a well organized multicenter-study. In rather short time reliable information concerning indication, compatibility and dosage can be received. The results of this project are similar to other observations dealing with DPA: Good therapeutical effect in primary generalized epilepsies independent of the seizure-type. Astonishing results influencing Lennox-Syndrome. In cases not treated before, Convulex shows at least the same effect than the "standard anticonvulsants" but less side effects, especially sedation. In those untreated "new-comers" therapeutical effect comes earlier than in cases of premedication. 20 to 50 mg/kg/day can be recommended in childhood. In rare cases the dosage was increased up to 120 mg/kg/day without problems.

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AustriaChildEpilepsyEpilepsy, AbsenceEpilepsy, Temporal LobeEpilepsy, Tonic-ClonicHumansValeratesValproic AcidEnglish AbstractJournal Article

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Ch Groh, F W Rosenmayr. 1976. [Austrian complex-study on dipropylacetate. Pediatric experiences].. https://pubmed.ncbi.nlm.nih.gov/814526/

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