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PubMed · 814605

Auto-immune disease.

G S Panayi
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Abstract

Auto-immune disease may result from the interaction of the genetic load of the individual, modification of self-tissue antigens by environmental agents such as virus or drugs and abnormalities of the immunological system itself such as the loss of controlling or suppressor T cells with age. In the majority of people the outcome is tolerance, maintenance of normal tissue architecture and function. In the unfortunate few the outcome is auto-immune disease, that is, failure to recognize "self".

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AnimalsAntigen-Antibody ReactionsAutoimmune DiseasesB-LymphocytesFreund's AdjuvantGuinea PigsHaplorhiniHaptensHumansImmune ToleranceImmunity, CellularImmunologic Deficiency SyndromesMiceRatsT-LymphocytesVirusesJournal ArticleReview

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G S Panayi. 1976. Auto-immune disease.. https://doi.org/10.1093/rheumatology%2F15.1.1

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