[Morphologic classification of glomerulonephritis revisited].

A A Ivanov; M A Pal'tsev; V V Serov; V A Varshavskiĭ

PubMed · 8204047

[Morphologic classification of glomerulonephritis revisited].

A A Ivanov·M A Pal'tsev·V V Serov·V A Varshavskiĭ

Abstract

The use of a wide spectrum of monoclonal antibodies allowed us to distinguish two groups of glomerulopathies: inflammatory (glomerulonephritis) and non-inflammatory. Glomerulus infiltration with inflammatory cells, glomerulus cell proliferation, heterogeneous composition and localization of the immune complex depositions even within one morphological form are characteristic of inflammatory glomerulopathies. A proliferative reaction is practically absent in non-inflammatory glomerulopathies, localization and deposits composition within one morphological form is homogeneous, the appearance of non-immune deposits containing only fibrin or low-density lipoproteins is typical. Specific podocyte marker, antigen of acute lymphoblastic leukemia, is practically absent at early stages of non-inflammatory glomerulopathies.

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Biomarkers Cell Division Glomerulonephritis Humans Inflammation English Abstract Journal Article

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A A Ivanov, M A Pal'tsev, V V Serov, V A Varshavskiĭ. [Morphologic classification of glomerulonephritis revisited].. https://pubmed.ncbi.nlm.nih.gov/8204047/

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