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Viscosity sensing with lamb-wave microsensor: dimethylsulfoxide solution viscosity as a function of temperature.

T K Eto·B J Costello·S W Wenzel·R M White·B Rubinsky
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Abstract

Recently, a new microsensor employing low-velocity ultrasonic Lamb waves was developed and demonstrated to be capable of measuring the viscosity of solutions in small volumes. The microsensor, when attached to a temperature-controlled stage, can measure viscosity as a function of temperature. In this investigation, the ultrasonic Lamb-wave oscillator is employed to experimentally measure the viscosity of dimethylsulfoxide (Me2SO) solutions as a function of temperature. The microsensor and the experimental procedure are described and results for 1M, 3M, and 5M Me2SO aqueous solutions are presented. Dimethylsulfoxide is a compound commonly employed as a cryoprotectant in cryopreservation, the low-temperature preservation of biological materials. The temperature dependence of viscosity obtained through this study can be used in determining the probability for ice nucleation in biological materials, a parameter of importance during cryopreservation.

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CalibrationCryopreservationDimethyl SulfoxideEvaluation Studies as TopicIceOscillometrySolutionsTemperatureUltrasonicsViscosityWaterJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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T K Eto, B J Costello, S W Wenzel, R M White, B Rubinsky. 1993. Viscosity sensing with lamb-wave microsensor: dimethylsulfoxide solution viscosity as a function of temperature.. https://doi.org/10.1115/1.2895494

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