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PubMed · 8241776

The community effect, dorsalization and mesoderm induction.

J B Gurdon·K Kato·P Lemaire
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Abstract

The community effect is an interaction among muscle progenitor cells of amphibian gastrula, and is necessary for the initiation of muscle-specific gene expression. Dorsalization provides a signal that can convert ventral mesoderm cells to a muscle fate. Neither process involves mesoderm-inducing molecules. We suggest that the developmental significance of the community effect is to generate homogeneous but clearly demarcated groups of cells from progenitor cells arranged in a continuous gradient of developmental potential.

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AnimalsEmbryonic InductionGastrulaMesodermMusclesJournal ArticleReview

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J B Gurdon, K Kato, P Lemaire. 1993. The community effect, dorsalization and mesoderm induction.. https://doi.org/10.1016/0959-437x(93)90104-w

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